Hydrochloric Acid → HCID 61504782, compound

HRID 505185Notes

Reaction equation

HRID 505185 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[CH2:20][O:21][CH3:22])[CH2:10][CH2:9]1)=O)(C)(C)C.Cl>O1CCOCC1>[CH3:22][O:21][CH2:20][C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=1[N:11]1[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 66744398HCID 66744398, compound

Product 1

HCID 61504782HCID 61504782, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent2×

Procedure

A solution of 4-(2-methoxymethyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester (prepared as described herein below) in dioxan was treated with 4 eq. of 4M HCl in dioxane and stirred at RT for 16 h. After neutralization, the mixture was completely evaporated to give the crude title compound.

Workup

  1. customAfter neutralization, the mixture was completely evaporated

Sources & evidence

ORD record
ord-e887fee0ffaa46aabd84644a9bdff2b3
Source dataset
uspto-grants-2010_08
Patent number
US07781436B2

Reaction notes

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