Hydrochloric Acid → N1,4,5-Trimethylbenzene-1,2-diamine

HRID 508768Notes

Reaction equation

HRID 508768 reaction equation
[CH3:1][NH:2][C:3]1[CH:8]=[C:7]([CH3:9])[C:6]([CH3:10])=[CH:5][C:4]=1[N+:11]([O-])=O.Cl>[Fe].CO>[CH3:1][NH:2][C:3]1[C:4]([NH2:11])=[CH:5][C:6]([CH3:10])=[C:7]([CH3:9])[CH:8]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 601943HCID 601943, compound

Product 1

HCID 591611N1,4,5-Trimethylbenzene-1,2-diamineYield 42%

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 887MethanolSolvent

Procedure

The title compound was prepared according to the procedure described in step-2 of Intermediate-28 by using N1,4,5-trimethyl-2-nitroaniline (0.350 g, 1.9 mmol), methanol (20 mL), Iron powder (1.75 g, 9.75 mmol), conc. HCl (5 mL) to afford 0.120 g of desired product.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-b810c01bfc624175b71a69de3921e038
Source dataset
uspto-grants-2015_08
Patent number
US09096545B2

Reaction notes

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