反应详情

To a stirring solution of compound 92 (0.159 g, 0.682 mmol) and triethylamine (0.2 mL, 1.435 mmol) in MeCN (10 mL) was added benzoyl chloride (0.10 mL, 0.862 mmol) and the reaction mixture was stirred for 2 h at room temperature. The reaction was diluted with ethyl acetate, washed with sat. aq. Na2CO3, water, brine, dried over Na2SO4, filtered and concentrated to afford the desired compound (0.196 g, 85%) as a colorless oil. LRMS (ESI): (calc) 337.41 (found) 338.35 (MH)+

1. washwashed with sat. aq. Na2CO3, water, brine
2. dry with materialdried over Na2SO4
3. filtrationfiltered
4. concentrationconcentrated