HCID 66798230, compound → HCID 66798061, compound

HRID 511061Notes

Reaction equation

HRID 511061 reaction equation
[OH:1][CH2:2][CH2:3][C:4]#[C:5][C:6]1[CH:19]=[C:18]2[C:9]([C:10]3[CH:11]=[CH:12][C:13]([OH:20])=[CH:14][C:15]=3[CH2:16][CH2:17]2)=[CH:8][CH:7]=1>C1COCC1>[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[CH:19]=[C:18]2[C:9]([C:10]3[CH:11]=[CH:12][C:13]([OH:20])=[CH:14][C:15]=3[CH2:16][CH2:17]2)=[CH:8][CH:7]=1

Participants

3

Reactant 1

HCID 66798230HCID 66798230, compound

Product 1

HCID 66798061HCID 66798061, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

7-(4-Hydroxybut-1-ynyl)-9,10-dihydrophenanthren-2-ol is dissolved in THF and hydrogenated to completion on palladium/active carbon catalyst. The catalyst is filtered off, the solvent is removed in vacuo, and the residue is recrystallised from toluene, giving 7-(4-hydroxybutyl)-9,10-dihydrophenanthren-2-ol as colourless crystals.

Workup

  1. filtrationThe catalyst is filtered off
  2. customthe solvent is removed in vacuo
  3. customthe residue is recrystallised from toluene

Sources & evidence

ORD record
ord-972c8aba42c74e89b73e9da14e1c0e56
Source dataset
uspto-grants-2015_08
Patent number
US09096795B2

Reaction notes

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