Benzyl Bromide → HCID 66930962, compound

HRID 511965Notes

Reaction equation

HRID 511965 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([OH:15])[CH:10]=1.C([O-])([O-])=O.[K+].[K+].[CH2:22](Br)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:10]=1

Participants

4

Reactant 3

HCID 7498Benzyl BromideHCID 11430Potassium CarbonateHCID 66931231HCID 66931231, compound

Product 1

HCID 66930962HCID 66930962, compound

Procedure

7-Bromo-1-(3-benzyloxy-phenyl)-heptane (10.2) was prepared as in 10.1 using 9.2 (0.4 g, 1.48 mmol), K2CO3 (0.612 g, 4.44 mmol) and benzyl bromide (0.278 g, 1.63 mmol). The title, compound (10.2) was isolated as a viscous liquid after purification by flash column chromatography (0.411 g, 77% yield).

Sources & evidence

ORD record
ord-75e0aded731d4bc9a5563fc60b473dd7
Source dataset
uspto-grants-2015_08
Patent number
US09102622B2

Reaction notes

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