Aminoacetaldehyde dimethyl acetal → HCID 44997787, compound

HRID 512103Notes

Reaction equation

HRID 512103 reaction equation
C([O:3][C:4](=O)[C:5]([NH:7][CH2:8][CH3:9])=[O:6])C.[CH3:11][O:12][CH:13]([O:16][CH3:17])[CH2:14][NH2:15]>CC(O)C>[CH3:11][O:12][CH:13]([O:16][CH3:17])[CH2:14][NH:15][C:4](=[O:3])[C:5]([NH:7][CH2:8][CH3:9])=[O:6]

Participants

4

Reactant 2

HCID 89728Aminoacetaldehyde dimethyl acetalHCID 3413435HCID 3413435, compound

Product 1

HCID 44997787HCID 44997787, compoundYield 80.5%

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

59.9 g (412.6 mM) of ethyl(ethylamino)(oxo)acetate and 45 ml (412.6 mM) of (2,2-dimethoxyethyl)amine in 480 ml of 2-propanol were stirred at room temperature for 16 h. A white precipitate was filtered, washed with 2-propanol and dried under vacuum, to give 67.8 g of N-(2,2-dimethoxyethyl)-N′-ethylethanediamide. Yield: 80.5%.

Workup

  1. filtrationA white precipitate was filtered
  2. washwashed with 2-propanol
  3. customdried under vacuum

Sources & evidence

ORD record
ord-906a573158c14fc890fa8e831f12f7bc
Source dataset
uspto-grants-2015_08
Patent number
US09102632B2

Reaction notes

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