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HRID513450

反应详情

EQUATION

反应方程式

HRID 513450 的结构方程式

REACTANTS

反应物

2
结构：Nc1cccc2cccnc12
HCID11359

8-Quinolinamine

C9H8N2

结构：COC(=O)c1cccc(S(=O)(=O)Cl)c1
HCID113339

Benzoic acid, 3-(chlorosulfonyl)-, methyl ester

C8H7ClO4S

PRODUCTS

生成物

1
结构：COC(=O)c1cccc(S(=O)(=O)Nc2cccc3cccnc23)c1
HCID31702993

未命名化合物

收率 64%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)c1ccncc1
催化剂HCID14284

N,N-Dimethylpyridin-4-amine

C7H10N2

PROCEDURE

实验过程

In the similar fashion using route 14 general procedure 27, 8-aminoquinoline (100 mg, 0.69 mmol), methyl 3-chlorosulfonylbenzoate (160 mg, 0.69 mmol) and DMAP (cat.) gave the title compound (150 mg, 64%) after purification by column chromatography with DCM as the eluent.