反应详情

In a similar fashion using route 14 general procedure 27, 5-fluoroquinolin-8-amine (Intermediate 50) (150 mg, 0.93 mmol), benzenesulfonyl chloride (196 mg, 1.11 mmol) and DMAP (cat) gave the title compound (170 mg, 61%) after column chromatography with DCM eluent.