HRID513507

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc(S(=O)(=O)Cl)c([N+](=O)[O-])c1

HCID87452

4-Methoxy-2-nitrobenzenesulphonyl chloride

C7H6ClNO5S

HCID140457

2-Methyl-8-aminoquinoline

C10H10N2

2 次

PRODUCTS

生成物

结构：COc1ccc(S(=O)(=O)Nc2cccc3ccc(C)nc23)c([N+](=O)[O-])c1

HCID23631949

未命名化合物

收率 51.8%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID14284

N,N-Dimethylpyridin-4-amine

C7H10N2

PROCEDURE

实验过程

In a similar fashion using route 14 general procedure 27, 2-methyl-quinolin-8-ylamine (Intermediate 22) (500 mg, 3.1 mmol) and 4-methoxy-2-nitrobenzenesulfonyl chloride (826 mg, 3.4 mmol) and DMAP (19 mg, 1.5 mmol) gave the title compound (600 mg, 51%).