反应详情

In a similar fashion using route 1 general procedure 4, 2-nitro-N-quinolin-8-yl-4-trifluoromethoxy-benzenesulfonamide (Intermediate 271) (500 mg, 1.21 mmol), SnCl2 (918 mg, 4.84 mmol), 6N HCl (5 drops) and EtOH (10 ml) gave the title compound (350 mg, 75%) which was used in the next step without further purification.