反应详情

In a similar fashion using route 51 general procedure 118, 12-chloro-9-fluoro-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide 503 (200 mg, 0.59 mmol), serinol (217 mg, 2.3 mmol) and NMP (2 ml) gave title compound (25 mg, 54%) after purification by column chromatography using DCM/MeOH:aq.NH3 (99.5:0.5:1 drop) as the eluent.