反应详情

温度

80 °C

2,2-Dimethyl-5-fluoromethyl-5-[2-(2-nitro-1H-imidazol-1-yl)ethyl]-1,3-dioxane was dissolved in 0.5 mL of acetonitrile, 0.5 mL of 1 mol/L hydrochloric acid was added thereto, and the mixture was stirred at 80° C. for 30 minutes. After completion of the reaction, the mixture was concentrated under vacuum to give a trace amount of 1-(3,3-dihydroxymethyl-4-fluorobutyl)-2-nitroimidazole.

1. customAfter completion of the reaction
2. concentrationthe mixture was concentrated under vacuum