Hydrochloric Acid → HCID 117831357, compound

HRID 515890Notes

Reaction equation

HRID 515890 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]2[C@H:20]([CH2:21][CH:22]([C:30]([N:32]3[CH2:37][CH2:36][O:35][CH2:34][CH2:33]3)=[O:31])[C:23]([O:25]C(C)(C)C)=[O:24])[CH2:19][C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[CH2:12]2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.Cl>O1CCOCC1>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([S:8]([N:11]2[C@H:20]([CH2:21][CH:22]([C:30]([N:32]3[CH2:33][CH2:34][O:35][CH2:36][CH2:37]3)=[O:31])[C:23]([OH:25])=[O:24])[CH2:19][C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[CH2:12]2)(=[O:10])=[O:9])=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 131733310HCID 131733310, compound

Product 1

HCID 117831357HCID 117831357, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent2×

Procedure

To a solution of 9.5 g (17.97 mmol) of the compound obtained in Step B in 40 mL of dioxane there are added, dropwise, 20 mL of a 4M solution of HCl in dioxane. The batch is stirred at ambient temperature for 48 hours and then the solution is concentrated to dryness. After drying, the expected product is obtained in the form of an oil.

Workup

  1. concentrationthe solution is concentrated to dryness
  2. customAfter drying

Sources & evidence

ORD record
ord-1b3c743a63b747fca9a93b840acaaa52
Source dataset
uspto-grants-2015_08
Patent number
US09108983B2

Reaction notes

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