反应详情

To a solution of 1,1-dimethylethyl 2,2-dimethyl-4-({1-[3-(trifluoromethyl)phenyl]-1H-tetrazol-5-yl}methyl)-1-piperazinecarboxylate (567 mg, 1.287 mmol, Intermediate 11) in methanol was added 4M hydrogen chloride in 1,4-Dioxane (7 ml, 28.0 mmol). The reaction mixture was stirred at room temperature for 1 hour.