反应详情

To a solution of 3-methyl-4-({1-[3-(trifluoromethyl)phenyl]-1H-tetrazol-5-yl}methyl)-2-piperazinone (100 mg, 0.294 mmol, Compound 32), in N,N-Dimethylformamide (DMF) (1.5 mL) was added sodium hydride (25.9 mg, 0.646 mmol). After stirring for 1 hour under argon, iodomethane (0.020 mL, 0.323 mmol) was added. The resulting reaction mixture was stirred under argon for 1 hour.

1. customThe resulting reaction mixture
2. stirringwas stirred under argon for 1 hour