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HRID51883

反应详情

EQUATION

反应方程式

HRID 51883 的结构方程式

REACTANTS

反应物

5
结构：CC(=O)Cl
HCID6367

Acetyl chloride

C2H3ClO

结构：CN1CCOCC1
HCID7972

4-Methylmorpholine

C5H11NO

结构：O=C(O)c1ccnc(Br)c1
HCID222701

2-bromoisonicotinic acid

C6H4BrNO2

结构：CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F
HCID9886157

Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)

C10H15F6N6OP

结构：COCCNc1ccc(OC)c2nc(N)sc12
HCID22736980

未命名化合物

PRODUCTS

生成物

1
结构：COCCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3ccnc(Br)c3)sc12
HCID22736982

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

3
结构：c1ccncc1
溶剂HCID1049

Pyridine

C5H5N

结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

2 次

PROCEDURE

实验过程

From 4-methoxy-N7-(2-methoxy-ethyl)-benzothiazole-2,7-diamine with pyridine and acetyl chloride in dichloromethane and THF, then treatment with 2-bromo-isonicotinic acid, HATU and N-methylmopholine in THF. ES-MS m/e (%): 481 (M{81Br}+H+, 100), 479 (M{79Br}+H+, 99).