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HRID520854

反应详情

EQUATION

反应方程式

HRID 520854 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：Nc1cc(Cl)ccc1S
HCID12000

2-Amino-4-chlorobenzenethiol

C6H6ClNS

结构：CC(C)(C)OC(=O)Nc1nc(CCl)cs1
HCID45117840

tert-Butyl [4-(chloromethyl)-1,3-thiazol-2-yl]carbamate

C9H13ClN2O2S

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)Nc1nc(CSc2ccc(Cl)cc2N)cs1
HCID86690989

未命名化合物

收率 100.7%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

Following General Procedure A, the title compound (588 mg, 67%) was prepared from 2-amino-4-chlorobenzenethiol (376 mg, 2.36 mmol), tert-butyl[4-(chloromethyl)-1,3-thiazol-2-yl]carbamate (391 mg, 1.57 mmol) and K2CO3 (1.08 g, 3.45 mmol) in DMF (10 ml).