反应详情

温度

120 °C

10 g (0.295 mol) of (2-bromobenzyl)diphenylamine are dissolved in 500 ml of dimethylformamide under protective atmosphere. 3.4 g (0.075 mol) of benzyltrimethylammonium bromide and 6.1 g (0.443 mol) of potassium carbonate are added to this solution. 0.99 g (0.004 mol) of Pd(OAC)2 is subsequently added under protective gas, and the mixture is stirred at 120° C. for 9 h. After this time, the reaction mixture is cooled to room temperature and extracted with dichloromethane. The combined organic phases are dried over Na2SO4 and evaporated. The residue is recrystallised from n-heptane. The yield is 6 g (80%).

1. temperatureAfter this time, the reaction mixture is cooled to room temperature
2. extractionextracted with dichloromethane
3. dry with materialThe combined organic phases are dried over Na2SO4
4. customevaporated
5. customThe residue is recrystallised from n-heptane