Tetrahydrofuran → HCID 131735570, compound

HRID 523462Notes

Reaction equation

HRID 523462 reaction equation
[N:1]12CC[N:4]([CH2:5][CH2:6]1)[CH2:3][CH2:2]2.[I:9][C:10]([I:15])([CH2:13][CH3:14])CC.[CH2:16]1[CH2:20]O[CH2:18][CH2:17]1>>[I-:9].[N:1]12[CH2:6][CH2:5][N:4]([CH2:3][CH2:2]1)[CH2:18][CH:17]2[CH2:16][CH2:20][CH2:14][CH2:13][CH2:10][I:15]

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 9237DabcoHCID 155803943,3-Diiodopentane

Product 1

HCID 131735570HCID 131735570, compound

Procedure

1,4-diazabicyclo[2.2.2]octane is suspended in THF. Diiodopentane is added dropwise and the mixture is refluxed overnight. The reaction mixture is filtered.

Workup

  1. temperaturethe mixture is refluxed overnight
  2. filtrationThe reaction mixture is filtered

Sources & evidence

ORD record
ord-eee7e29f53ff443ca50c2ed18a07e937
Source dataset
uspto-grants-2016_05
Patent number
US09339480B2

Reaction notes

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