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HRID524720

反应详情

EQUATION

反应方程式

HRID 524720 的结构方程式

REACTANTS

反应物

3
结构：CCOC(=O)CC(C)=O
HCID8868

Ethyl acetoacetate

C6H10O3

结构：O=Cc1ccc(Cl)cc1Cl
HCID13404

2,4-Dichlorobenzaldehyde

C7H4Cl2O

结构：Cl.N=C(N)c1ncccc1F
HCID22027837

3-Fluoropyridine-2-carboximidamide--hydrogen chloride (1/1)

C6H7ClFN3

PRODUCTS

生成物

1
结构：CCOC(=O)C1=C(C)NC(c2ncccc2F)=NC1c1ccc(Cl)cc1Cl
HCID90043012

未命名化合物

收率 54%

PROCEDURE

实验过程

3-fluoropicolinimidamide hydrochloride (5.53 g, 31.5 mmol) was reacted with 2,4-dichlorobenzaldehyde (5.51 g, 31.5 mmol) and ethyl 3-oxobutanoate (4.1 g, 31.5 mmol) according to the procedure as described in Example 1, Step A to give the title compound as a yellow solid (6.94 g, 54%). The compound was characterized by the following spectroscopic data: