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HRID52591

反应详情

EQUATION

反应方程式

HRID 52591 的结构方程式

REACTANTS

反应物

3
结构：CCCC(CCC)C(=O)O
HCID3121

Valproic acid

C8H16O2

结构：CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F
HCID2733207

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

C11H16BF4N5O

结构：NC(=N[N+](=O)[O-])NCCC[C@@H](N)C(=O)NCc1ccc(O)cc1
HCID136381090

未命名化合物

PRODUCTS

生成物

1
结构：CCCC(CCC)C(=O)N[C@H](CCCNC(N)=N[N+](=O)[O-])C(=O)NCc1ccc(O)cc1
HCID136381110

未命名化合物

收率 65%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

Prepared analogously to Example 5d), but using tetrahydrofuran instead of acetonitrile, from (R)-N5 -[amino(nitroimino)methyl]-N-[(4-hydroxyphenyl)methyl]-ornithinamide, 2-propyl-pentanoic acid and TBTU in a yield of 65% of theory. Colourless crystalline substance which was further processed without purification.

WORKUP

后处理

  1. customPrepared analogously to Example 5d), but
  2. customColourless crystalline substance which was further processed without purification