Boron trifluoride etherate → HCID 71152494, compound

HRID 526735Notes

Reaction equation

HRID 526735 reaction equation
[CH2:1]([N:8]([CH2:14][C:15]#[C:16][CH2:17][OH:18])[C:9](=[O:13])[O:10][CH2:11][CH3:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.B(F)(F)F.CC[O:25]CC>C(#N)C.O.C([O-])(=O)C.[Hg+2].C([O-])(=O)C>[CH2:1]([N:8]([CH2:14][CH2:15][C:16](=[O:25])[CH2:17][OH:18])[C:9](=[O:13])[O:10][CH2:11][CH3:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

6

Reactant 2

HCID 8000Boron trifluoride etherateHCID 71152056HCID 71152056, compound

Product 1

HCID 71152494HCID 71152494, compound

Reagents, catalysts & solvents 3

HCID 15337Mercuric acetateCatalystHCID 962WaterSolventHCID 6342AcetonitrileSolvent

Conditions

Temperature
90 °C

Procedure

A mixture of ethyl benzyl(4-hydroxybut-2-ynyl)carbamate (0.05 g, 0.202 mmol), mercury(II) acetate (6.44 mg, 0.020 mmol) and boron trifluoride etherate (5.12 μl, 0.040 mmol) in Acetonitrile (0.5 ml) and Water (0.250 ml) stirred at 90° C. in wheaton vial for 30 min. By HPLC-MS the main peak corresponds to expected product.

Sources & evidence

ORD record
ord-8d41dc2a3ddb457f90d1c3e4bf4b78bb
Source dataset
uspto-grants-2016_05
Patent number
US09346751B2

Reaction notes

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