HCID 86714714, compound → HCID 68320279, compound

HRID 529227Notes

Reaction equation

HRID 529227 reaction equation
C([O:8][C:9]([C:11]1[S:12][C:13]([CH:16]=[CH:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])=[CH:14][CH:15]=1)=[O:10])C1C=CC=CC=1>CO.C(Cl)(Cl)Cl.[OH-].[Pd+2].[OH-]>[C:21]([O:20][C:18]([CH2:17][CH2:16][C:13]1[S:12][C:11]([C:9]([OH:10])=[O:8])=[CH:15][CH:14]=1)=[O:19])([CH3:24])([CH3:22])[CH3:23]

Participants

5

Reactant 1

HCID 86714714HCID 86714714, compound

Product 1

HCID 68320279HCID 68320279, compound

Reagents, catalysts & solvents 3

HCID 9942167Palladium hydroxideCatalystHCID 887MethanolSolventHCID 6212ChloroformSolvent

Procedure

The compound (0.5 g, 1.45 mmol) obtained in step 1 was dissolved in methanol (5 mL) and chloroform (0.5 mL), palladium hydroxide (0.1 g) was added, and the mixture was dried at room temperature under a hydrogen atmosphere overnight. The reaction mixture was filtered through celite, and the solvent was evaporated under reduced pressure to give the title compound.

Workup

  1. customthe mixture was dried at room temperature under a hydrogen atmosphere overnight
  2. filtrationThe reaction mixture was filtered through celite
  3. customthe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-8509b9e8d46841a09c8dd7d44d88bfae
Source dataset
uspto-grants-2016_05
Patent number
US09346821B2

Reaction notes

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