反应详情

To a solution of compound 2 in Scheme 4-3 (98 mg, 0.8 mmol) in DCM (10 mL) was added TMSCN (0.2 mL) at room temperature. After the mixture was stirred for 30 min, diethylcarbamic chloride (0.2 mL) was added, and stirred for 24 h. The mixture was concentrated and the residue was purified by combi-flash (MeOH/H2O (NH4HCO3)) to give a white solid. LCMS (ESI) m/z=134 (M+H)+.

1. stirringstirred for 24 h
2. concentrationThe mixture was concentrated
3. customthe residue was purified by combi-flash (MeOH/H2O (NH4HCO3))
4. customto give a white solid