反应详情

To 4-chloro-5H-pyrrolo[3,2-d]pyrimidine (100 mg), tetrahydrofuran (5 mL) was added, and N-bromosuccinimide (116 mg) was further added thereto, followed by stirring for 1 hour. After completion of the reaction, the reaction mixture was mixed with ethyl acetate and washed with water. The washed mixture was dried over anhydrous sodium sulfate, and filtered and distilled under reduced pressure to obtain the title compound.

1. customAfter completion of the reaction
2. washwashed with water
3. dry with materialThe washed mixture was dried over anhydrous sodium sulfate
4. filtrationfiltered
5. distillationdistilled under reduced pressure