反应详情

温度

120 °C

A mixture of 3,5-dimethyl-1,2,4-triazole (6.0 parts; 0.062 mol ex (b) above) and 1-bromodecane (14.4 parts; 0.065 mol) in dimethylformamide (16 ml) was heated together at 120° C. for 23 hours. The cooled reaction mixture was diluted with water (100 ml), a solution of sodium hydroxide (2.62 parts; 0.065 mol) in water (100 ml) added, and the product extracted into ether (3×50 ml). After drying over magnesium sulphate the solution was evaporated to yield a pale yellow oil (3.3 parts; 22% theory).

1. customThe cooled reaction mixture
2. extractionthe product extracted into ether (3×50 ml)
3. dry with materialAfter drying over magnesium sulphate the solution
4. customwas evaporated
5. customto yield a pale yellow oil (3.3 parts; 22% theory)