Hydrochloric Acid → HCID 66634127, compound

HRID 536566Notes

Reaction equation

HRID 536566 reaction equation
[CH3:1][O:2][C:3](=[O:28])/[CH:4]=[CH:5]/[C:6]1[CH:10]=[C:9]([CH3:11])[N:8]([CH2:12][C:13]2[CH:18]=[C:17]([Cl:19])[CH:16]=[CH:15][C:14]=2[O:20]CC2C=CC=CC=2)[N:7]=1.Cl>C(O)(=O)C.O=[Pt]=O>[CH3:1][O:2][C:3](=[O:28])[CH2:4][CH2:5][C:6]1[CH:10]=[C:9]([CH3:11])[N:8]([CH2:12][C:13]2[CH:18]=[C:17]([Cl:19])[CH:16]=[CH:15][C:14]=2[OH:20])[N:7]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 68641221HCID 68641221, compound

Product 1

HCID 66634127HCID 66634127, compound

Reagents, catalysts & solvents 2

HCID 345198Adams' catalystCatalystHCID 176Acetic AcidSolvent

Procedure

A stirred solution of unsaturated ester 14, (1.2 g, 2.9 mmol) and PtO2, 0.12 g in acetic acid (25 mL) and conc. HCl (5 mL) was hydrogenated at room temperature for 16 hours. The catalyst was removed by filtration through Hyflo and the filtrate was evaporated to dryness to afford the saturated ester 15, 0.8 g (90%).

Workup

  1. customThe catalyst was removed by filtration through Hyflo
  2. customthe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-a85c876d00964f58928a91422017188b
Source dataset
uspto-grants-2014_10
Patent number
US08859606B2

Reaction notes

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