反应详情

Water (0.25 ml) was added to this silica gel supporting scandium (75 mg), and while stirring, 4-phenyl-2-butanone (0.25 mmol) and tetraallyltin (0.125 mmol) were continuously added. The mixture was stirred at 40° C. for 24 hours. The mixture was returned to room temperature, and then was extracted four times by a decantation method using hexane. The solvent was distilled off under reduced pressure, and then the residue was purified by silica gel thin layer chromatography, to obtain the target product, 1-phenyl-3-buten-1-ol. Yield 98%.

1. stirringThe mixture was stirred at 40° C. for 24 hours
2. customwas returned to room temperature
3. extractionwas extracted four times by a decantation method
4. distillationThe solvent was distilled off under reduced pressure
5. customthe residue was purified by silica gel thin layer chromatography