Methanesulfonyl chloride → 2-Azidopentyl methanesulfonate

HRID 539532Notizen

Reaktionsgleichung

[N:1]([CH2:4][CH2:5][CH2:6][CH2:7]CO)=[N+:2]=[N-:3].S(Cl)(C)(=O)=O.[CH3:15][S:16]([O:19][CH2:20]CN=[N+]=[N-])(=[O:18])=[O:17]>>[CH3:15][S:16]([O:19][CH2:20][CH:4]([N:1]=[N+:2]=[N-:3])[CH2:5][CH2:6][CH3:7])(=[O:18])=[O:17]

Komponenten

Edukt 3

HCID 31297Methanesulfonyl chloride

HCID 108663585-Azidopentanol

HCID 112751972-Azidoethyl methanesulfonate

Produkt 1

HCID 866750852-Azidopentyl methanesulfonate

Versuchsvorschrift

Reaction of 5-azidopentanol (1.1 g, 8.53 mmol) and mesyl chloride (0.98 mL, 12.79 mmol) within 3 h as described for synthesis of 156a gave compound 156d (1.54 g) as a crude colorless oil.

Quellen und Nachweise

ORD-Eintrag: ord-d946bfd704e0410b9c55cbe4321e77ed
Quelldatensatz: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08871728B2

Notizen zur Reaktion

Wird geladen…