Diethyl (ethoxymethylene)malonate → HCID 178469633, compound

HRID 544399Notes

Reaction equation

CCO[CH:4]=[C:5]([C:11]([O:13]CC)=O)[C:6]([O:8][CH2:9][CH3:10])=[O:7].[CH3:16][O:17][C:18]1[CH:19]=[C:20]([CH:22]=[CH:23][CH:24]=1)[NH2:21].C1(OC2C=CC=CC=2)C=CC=CC=1>>[CH3:16][O:17][C:18]1[CH:19]=[C:20]2[C:22]([C:11]([OH:13])=[C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])[CH:4]=[N:21]2)=[CH:23][CH:24]=1

Participants

Reactant 3

HCID 6871Diethyl (ethoxymethylene)malonate

HCID 7583Diphenyl Ether

HCID 108243-Methoxyaniline

Product 1

HCID 178469633HCID 178469633, compound

Procedure

Using the procedure of Example 2, ethyl ethoxymethylene malonate and 3-methoxy-aniline were reacted and treated with phenyl oxide to obtain ethyl 7-methoxy-4-hydroxy-3-quinoline-carboxylate melting at >260° C.

Workup

customwere reacted

Sources & evidence

ORD record: ord-1005b4e0e70445d891b0f01c33931f1b
Source dataset: uspto-grants-1984_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04450166

Reaction notes

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