tert-butyl N'-(5-chloro-2-cyclohexyl-pentanoyl)-hydrazinecarboxylate → 5-Chloro-2-cyclohexyl-valeric acid hydrazide hydrochloride
Reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][CH:5]([CH:17]1[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1)[C:6]([NH:8][NH:9]C(OC(C)(C)C)=O)=[O:7]>Cl.O1CCOCC1>[ClH:1].[Cl:1][CH2:2][CH2:3][CH2:4][CH:5]([CH:17]1[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1)[C:6]([NH:8][NH2:9])=[O:7]Participants
4
Procedure
tert-Butyl N′-(5-chloro-2-cyclohexyl-pentanoyl)-hydrazinecarboxylate (155 mg) was dissolved in a solution of 4 N hydrogen chloride in dioxane (2 ml), and the reaction solution was stirred at room temperature for one hour. The reaction solution was concentrated under reduced pressure to obtain 144 mg of the title compound. The property value of the compound is as follows.
Workup
- concentrationThe reaction solution was concentrated under reduced pressure
Sources & evidence
- ORD record
- ord-3003b35eed6748cfa68010ac9fd15804
- Source dataset
- uspto-grants-2011_05
- Patent number
- US07935815B2
Reaction notes
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