Sodium Iodide → HCID 86750357, compound

HRID 54835Notes

Reaction equation

HRID 54835 reaction equation
[Na+].[NH2:2][C:3]([O:5][CH2:6][CH:7]1[O:11][CH2:10][CH:9]([S:12][C:13]2[CH:19]([CH3:20])[CH:18]3[N:15]([C:16](=[O:24])[CH:17]3[CH:21]([OH:23])[CH3:22])[C:14]=2[C:25]([O-:27])=[O:26])[CH2:8]1)=[O:4].[C:28]([O:34][CH2:35]Cl)(=[O:33])[C:29]([CH3:32])([CH3:31])[CH3:30].C(=O)(O)[O-].[Na+].[I-].[Na+]>>[CH3:30][C:29]([CH3:32])([CH3:31])[C:28](=[O:33])[O:34][CH2:35][O:26][C:25]([C:14]1[N:15]2[CH:18]([CH:19]([CH3:20])[C:13]=1[S:12][CH:9]1[CH2:8][CH:7]([CH2:6][O:5][C:3]([NH2:2])=[O:4])[O:11][CH2:10]1)[CH:17]([CH:21]([OH:23])[CH3:22])[C:16]2=[O:24])=[O:27]

Participants

5

Reactant 4

HCID 5238Sodium IodideHCID 87885Chloromethyl pivalateHCID 516892Sodium BicarbonateHCID 131719840HCID 131719840, compound

Product 1

HCID 86750357HCID 86750357, compound

Procedure

The title compound is prepared by the procedure of Example 407 using 0.460 g of product from Example 21, 0.24 ml of chloromethyl pivalate, 0.189 g of sodium bicarbonate and 0.252 g of sodium iodide to give after chromatography 0.32 g of the desired product.

Sources & evidence

ORD record
ord-d3a3b1eeebe04963a7447f94ecf0b7fc
Source dataset
uspto-grants-1997_04
Patent number
US05623081

Reaction notes

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