Hydrazine hydrate (1:1) → 2,2-Dimethyl-4-pentenohydrazide

HRID 550545Notes

Reaction equation

HRID 550545 reaction equation
[CH3:1][C:2]([CH3:10])([CH2:7][CH:8]=[CH2:9])[C:3](OC)=[O:4].O.[NH2:12][NH2:13]>CO>[CH3:1][C:2]([CH3:10])([CH2:7][CH:8]=[CH2:9])[C:3]([NH:12][NH2:13])=[O:4]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 11768679Methyl 2,2-dimethylpent-4-enoate

Product 1

HCID 576918522,2-Dimethyl-4-pentenohydrazide

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Conditions

Temperature
60 °C

Procedure

To a solution of methyl 2,2-dimethyl-4-pentenoate (1 g) in MeOH (2 ml) was added hydrazine monohydrate (2.7 ml). The solution was heated in a close microwave vial at 60° C. for 12 h. Volatiles were evaporated in vacuo to give 1 g of the title compound as a yellow pale foam, which was used without further purification.

Workup

  1. customVolatiles were evaporated in vacuo

Sources & evidence

ORD record
ord-6389608f00bc4024aa9b779acd323f32
Source dataset
uspto-grants-2011_05
Patent number
US07947683B2

Reaction notes

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