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HRID550888

反应详情

EQUATION

反应方程式

HRID 550888 的结构方程式

REACTANTS

反应物

5
结构：NO
HCID787

Hydroxylamine

H3NO

结构：O=Cc1c[nH]c2ccccc12
HCID10256

1H-Indole-3-carboxaldehyde

C9H7NO

结构：N#Cc1ccc(F)cc1
HCID14517

4-Fluorobenzonitrile

C7H4FN

结构：[N-]=[N+]=[N-].[Na+]
HCID33557

未命名化合物

结构：c1nnn[nH]1
HCID178418441

未命名化合物

PRODUCTS

生成物

1
结构：CCc1c(C)nc2cccc(C)n2c1=O
HCID93406

3-Ethyl-2,6-dimethyl-4H-pyrido[1,2-a]pyrimidin-4-one

C12H14N2O

PROCEDURE

实验过程

XO-CH145 was prepared by coupling of indole-3-carboaldehyde and 4-fluorobenzonitrile in a similar manner to the third step of the above 1. XO-CH147 was prepared by converting XO-CH145 into a tetrazole derivative using sodium azide, followed by cyanation using hydroxylamine to give XO-CH150 (the following scheme).

WORKUP

后处理

  1. customXO-CH147 was prepared