反应详情

1.50 g (9.08 mmol) methyl 4-amino-3-methyl-benzoate are dissolved in 250 ml dioxane combined with 1.3 ml (10.7 mmol) trichloromethyl-chloroformate and refluxed for 5.5 hours with stirring. Then the mixture is evaporated down i. vac. and the residue is further reacted without any more purification.

1. temperaturerefluxed for 5.5 hours
2. customThen the mixture is evaporated down i
3. customand the residue is further reacted without any more purification