HRID55134

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID24758

Sodium hydride

HNa

HCID123570

Thiophene-3-methanol

C5H6OS

HCID12175136

4-Pyridinamine, 2,6-dichloro-N,N-dimethyl-

C7H8Cl2N2

PRODUCTS

生成物

HCID19957407

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8028

Tetrahydrofuran

C4H8O

2 次

PROCEDURE

实验过程

To a solution of 3-thiophenemethanol (0.526 g, 0.0042×1.1 mol) in 10 ml of dry tetrahydrofuran, sodium hydride (0.335 g, (ca.60% in mineral oil), 0.0042×2.0 mol) was added. After the bubbling ceased, a solution of 2,6-dichloro-4-dimethylaminopyridine (0.8 g, 0.0042 mol) in 20 ml of dry tetrahydrofuran was added dropwise at room temperature.