Ammonium Acetate → HCID 66924664, compound

HRID 554212Notes

Reaction equation

HRID 554212 reaction equation
[C:1]([CH:4]([CH:10](C)[C:11](=O)[C:12]1[CH:16]=[CH:15][S:14][CH:13]=1)[C:5]([O:7][CH2:8][CH3:9])=[O:6])(=O)[CH3:2].C([O-])(=O)C.[NH4+:23]>>[CH3:2][C:1]1[NH:23][C:11]([C:12]2[CH:16]=[CH:15][S:14][CH:13]=2)=[CH:10][C:4]=1[C:5]([O:7][CH2:8][CH3:9])=[O:6]

Participants

3

Reactant 2

HCID 517165Ammonium AcetateHCID 66924672HCID 66924672, compound

Product 1

HCID 66924664HCID 66924664, compoundYield 96.3%

Procedure

Using ethyl 2-acetyl-3-methyl-4-oxo-4-(3-thienyl)butanoate (1.86 g) and ammonium acetate (626 mg), a procedure as in Reference Example 14 was performed to give the title compound as a brown oil (yield 1.57 g, 91%).

Sources & evidence

ORD record
ord-ffa2e79740bb4803b23ad0b06a460de7
Source dataset
uspto-grants-2011_11
Patent number
US08048909B2

Reaction notes

Loading…