4-Tert-butylbenzene-1,2-diamine → HCID 11362786, compound

HRID 555395Notes

Reaction equation

HRID 555395 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([NH2:11])=[C:7]([NH2:12])[CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[C:13]([C:17]1[CH:34]=[CH:33][CH:32]=[CH:31][C:18]=1[O:19][C:20]1[C:25]([N:26]=[C:27]=S)=[CH:24][CH:23]=[C:22]([O:29][CH3:30])[N:21]=1)([CH3:16])([CH3:15])[CH3:14]>ClCCCl>[C:1]([C:5]1[CH:10]=[CH:9][C:8]2[N:11]=[C:27]([NH:26][C:25]3[C:20]([O:19][C:18]4[CH:31]=[CH:32][CH:33]=[CH:34][C:17]=4[C:13]([CH3:16])([CH3:15])[CH3:14])=[N:21][C:22]([O:29][CH3:30])=[CH:23][CH:24]=3)[NH:12][C:7]=2[CH:6]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 4327084-Tert-butylbenzene-1,2-diamineHCID 59857516HCID 59857516, compound

Product 1

HCID 11362786HCID 11362786, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Procedure

To a solution of 4-(tert-butyl)-1,2-diaminobenzene (20 mg, 0.12 mmol) in DCE (1 mL) was slowly added 2c (19 mg, 0.06 mmol). The reaction was stirred 18 h at rt and concentrated. The crude mixture containing 2d and 2d′ was used in the next step without further purification.

Workup

  1. concentrationconcentrated
  2. additionThe crude mixture containing 2d and 2d′
  3. customwas used in the next step without further purification

Sources & evidence

ORD record
ord-73980c66a9184a70a27842c939169a66
Source dataset
uspto-grants-2011_11
Patent number
US08053450B2

Reaction notes

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