Hydrochloric Acid → HCID 86652390, compound

HRID 556732Notes

Reaction equation

HRID 556732 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[N:10]1[CH:14]=[CH:13][CH:12]=[C:11]1[CH:15]=[CH:16][CH:17]1OCC[O:18]1)([O-:3])=[O:2].Cl>C(OCC)C>[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[N:10]1[CH:14]=[CH:13][CH:12]=[C:11]1[CH:15]=[CH:16][CH:17]=[O:18])([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 66991975HCID 66991975, compound

Product 1

HCID 86652390HCID 86652390, compoundYield 91%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of 2.6 g (9.1 mmol) 3a in 50 ml diethyl ether was stirred with 10% aqueous HCl for 1 hour. The reaction mixture was washed with 5% NaHCO3, dried over NaHCO3. After evaporation of the solvent, 2 g (91%) of 4a was obtained.

Workup

  1. washThe reaction mixture was washed with 5% NaHCO3
  2. dry with materialdried over NaHCO3
  3. customAfter evaporation of the solvent

Sources & evidence

ORD record
ord-920ab06a6d5947e3b39d29e3fd37c445
Source dataset
uspto-grants-2011_11
Patent number
US08058306B2

Reaction notes

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