Triethylamine → HCID 178486563, compound

HRID 557130Notes

Reaction equation

HRID 557130 reaction equation
[I-:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][C:13]=1[O:14][CH3:15])[N+:10]([CH3:16])=[C:9]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[N:8]=[C:7]2SC.[I-].[CH3:26][C:27]1[S:28][C:29]2[CH:36]=[CH:35][CH:34]=[CH:33][C:30]=2[N+:31]=1[CH3:32].C(N(CC)CC)C>CN(C)C=O>[I-:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][C:13]=1[O:14][CH3:15])[N:10]([CH3:16])[C:9]([C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1)=[N:8][C:7]2=[CH:26][C:27]1[S:28][C:29]2[CH:36]=[CH:35][CH:34]=[CH:33][C:30]=2[N+:31]=1[CH3:32]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 4591212,3-Dimethylbenzo[d]thiazol-3-ium iodideHCID 669913456,7-Dimethoxy-1-methyl-4-methylsulfanyl-2-phenyl-quinazolin-1-ium iodide

Product 1

HCID 178486563HCID 178486563, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
80 °C

Procedure

500 mg (1.10 mmol) 6,7-Dimethoxy-1-methyl-4-methylsulfanyl-2-phenyl-quinazolin-1-ium iodide and 320 mg (1.10 mmol) 2,3-Dimethyl-benzothiazol-3-ium iodide were dissolved in 200 ml dimethylformamide and 445 mg (0.61 ml, 4.40 mmol) triethylamine were added. The solution was stirred for 1 h at 80° C., filtrated and the residue is washed with water and methanol.

Workup

  1. filtrationfiltrated
  2. washthe residue is washed with water and methanol

Sources & evidence

ORD record
ord-26adb8e67e70425cbca90f2c480d318b
Source dataset
uspto-grants-2011_11
Patent number
US08058431B2

Reaction notes

Loading…