Nitric Acid → 2,3-Dimethoxy-6-nitrobenzaldehyde

HRID 557147Notes

Reaction equation

HRID 557147 reaction equation
[CH3:1][O:2][C:3]1[C:10]([O:11][CH3:12])=[CH:9][CH:8]=[CH:7][C:4]=1[CH:5]=[O:6].[N+:13]([O-])([OH:15])=[O:14]>O>[CH3:1][O:2][C:3]1[C:10]([O:11][CH3:12])=[CH:9][CH:8]=[C:7]([N+:13]([O-:15])=[O:14])[C:4]=1[CH:5]=[O:6]

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 665812,3-Dimethoxybenzaldehyde

Product 1

HCID 71721272,3-Dimethoxy-6-nitrobenzaldehyde

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

50.0 g (301 mmol) 2,3-Dimethoxy-benzaldehyd (Aldrich) were slowly added to nitric acid at 0° C. The reaction mixture was stirred for 5 minutes, diluted with water until no further precipitate was obtained. After filtration the residue was washed with methanol.

Workup

  1. customwas obtained
  2. filtrationAfter filtration the residue
  3. washwas washed with methanol

Sources & evidence

ORD record
ord-c527207b313145dc8119198982e0cd7d
Source dataset
uspto-grants-2011_11
Patent number
US08058431B2

Reaction notes

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