反应详情

The product of step (vii) (4 g) was suspended in acetonitrile (40 ml) and 4-(3-aminopropyl)morpholine (15 ml) was added. The mixture was stirred under reflux for 14 h. then the mixture evaporated under reduced pressure. The residue was purified by RPHPLC. Yield 3.59 g.

1. temperatureunder reflux for 14 h.
2. customthe mixture evaporated under reduced pressure
3. customThe residue was purified by RPHPLC