反应详情

The product of step (vi) (29.8 g) was dissolved in MeOH (60 ml) and treated with 4M hydrogen chloride in dioxane (60 ml). The mixture was stirred at rt for 2 hours, cooled to 0° C. and neutralised with 3.5% aqueous ammonia solution. The solid was filtered off, washed with water then MeOH and dried Yield 27.2 g.

1. filtrationThe solid was filtered off
2. washwashed with water
3. dry with materialMeOH and dried Yield 27.2 g