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HRID562604

反应详情

EQUATION

反应方程式

HRID 562604 的结构方程式

REACTANTS

反应物

2
结构：O
HCID962

Water

H2O

结构：CC(C)[O-].Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1
HCID86630109

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1
HCID3062316

Dasatinib

C22H26ClN7O2S

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

Dasatinib i-propanolate (form A3, 4.74 g) was dissolved in DMF (23.7 ml) at 100° C. After water (23.7 ml) was added at 100° C. The suspension was cooled to room temperature. The product was filtered off, washed with water (3×) and dried on the filter.

WORKUP

后处理

  1. filtrationThe product was filtered off
  2. washwashed with water (3×)
  3. customdried on the filter