反应详情

N-[1-(4-{2-[4-(2-Fluoro-benzyloxy)-2-oxo-2H-pyridin-1-yl]-ethyl}-benzyl)-piperidin-4-yl]-acetamide is prepared as example 9.1c from 80 mg (0.19 mmol) 1-[2-(4-bromomethyl-phenyl)ethyl]-4-(2-fluoro-benzyloxy)-1H-pyridin-2-one (example 9.1b), 41 mg (0.29 mmol) N-piperidin-4-yl-acetamide and 84 μL (0.48 mmol) N-ethyl-diisopropylamine as base.