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HRID564376

反应详情

EQUATION

反应方程式

HRID 564376 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(N)cn1
HCID81121

Pyridine, 5-amino-2-methoxy-

C6H8N2O

结构：COc1ccc(N2CCC(N3CC[C@@H](NC(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)cn1
HCID16722463

未命名化合物

PRODUCTS

生成物

1
结构：NC(=O)c1cccc(C(F)(F)F)c1
HCID74535

m-(Trifluoromethyl)benzamide

C8H6F3NO

PROCEDURE

实验过程

N-[2-({3R)-1-[1-(3-ethoxyphenyl)piperidin-4-yl]pyrrolidin-3-yl}amino)-2-oxoethyl]-3-(trifluoromethyl)benzamide was synthesized in similar fashion to N-[2-({(3R)-1-[1-(6-methoxypyridin-3-yl)piperidin-4-yl]pyrrolidin-3-yl}amino)-2-oxoethyl]-3-(trifluoromethyl)benzamide, substituting 3-ethoxyaniline for 6-methoxypyridin-3-amine. The crude product was purified by preparative HPLC. MS m/z: 519 (M+1).

WORKUP

后处理

  1. customThe crude product was purified by preparative HPLC