Hydrogen chloride-ethyl acetate → HCID 88145729, compound

HRID 566421Notes

Reaction equation

HRID 566421 reaction equation
[ClH:1].C(OCC)(=O)C.[O:8]1[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][CH2:16][NH:17][C:18]([O:20][CH2:21][CH:22]2[CH:27]([N:28]([CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH3:48])[CH:29]=[O:30])[CH2:26][CH:25]=[CH:24][CH2:23]2)=[O:19])[CH2:10][CH2:9]1>C(OCC)(=O)C>[ClH:1].[O:8]1[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][CH2:16][NH:17][C:18]([O:20][CH2:21][CH:22]2[CH:27]([N:28]([CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH3:48])[CH:29]=[O:30])[CH2:26][CH:25]=[CH:24][CH2:23]2)=[O:19])[CH2:10][CH2:9]1

Participants

4

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 88145730HCID 88145730, compound

Product 1

HCID 88145729HCID 88145729, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4N Hydrochloric acid/ethyl acetate solution (0.26 ml) was added to a solution of [6-[[N-(3-morpholinopropyl)carbamoyloxy]methyl]-3-cyclohexenyl]-N-octadecylformamide (0.30 g) in ethyl acetate (4 ml). After being stirred for 10 minutes at room temperature, the reaction mixture was concentrated. The residue was crystallized with ethyl acetate, thereby yielding the entitled compound (0.26 g) as white crystals.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was crystallized with ethyl acetate

Sources & evidence

ORD record
ord-2cf799600c7a418eb44b985b8239b9d7
Source dataset
uspto-grants-2001_01
Patent number
US06174885B1

Reaction notes

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