反应详情

Following the procedure of Example 52, 2-benzyloxy-5-cyano-6-(pyrrolidin)-1-yl)-benzo[de]isoquinoline-1,3-dione (0.15 g, 0.33 mmol, from Example B2) and a 1.0 M solution of boron tris(trifluoroacetate) in TFA (2 mL) was reacted to give 0.070 g of the title compound, mp 247-248° C.