反应详情

7-Nitro-2-(2,6-difluoro-phenyl)-benzo[d][1,3]oxazin-4-one (0.10 g) was dissolved in acetic acid (10 mL) under N2, PtO2 (5 mg) was added and the mixture was hydrogenated with H2 gas. Reaction time 1 day. The reaction mixture was filtered through Hyflo®, which was rinsed afterwards with ethyl acetate. The combined organic phases were evaporated to dryness and subsequently treated three times with toluene followed by evaporation.

1. customReaction time 1 day
2. filtrationThe reaction mixture was filtered through Hyflo®, which
3. washwas rinsed afterwards with ethyl acetate
4. customThe combined organic phases were evaporated to dryness
5. additionsubsequently treated three times with toluene
6. customfollowed by evaporation