Tributylstannane → HCID 54528940, compound

HRID 569018Notes

Reaction equation

HRID 569018 reaction equation
[CH2:1]([C:4]1([CH2:15][N:16]2[CH:20]=[CH:19][N:18]=[CH:17]2)[S:8][C:7]2[CH:9]=[C:10]([Cl:13])[CH:11]=[CH:12][C:6]=2[CH:5]1Cl)[CH:2]=[CH2:3].C([SnH](CCCC)CCCC)CCC>C1(C)C=CC=CC=1>[CH2:1]([C:4]1([CH2:15][N:16]2[CH:20]=[CH:19][N:18]=[CH:17]2)[S:8][C:7]2[CH:9]=[C:10]([Cl:13])[CH:11]=[CH:12][C:6]=2[CH2:5]1)[CH:2]=[CH2:3]

Participants

4

Reactant 2

HCID 5948TributylstannaneHCID 56622354HCID 56622354, compound

Product 1

HCID 54528940HCID 54528940, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Heat a reaction mixture of 1.4 g (4.3 mmoles) of the title compound of Example 7 and 2.5 g (8.5 mmoles) of tri(n-butyl)tin hydride in 20 mL of toluene at reflux overnight. Evaporate to give a residue. Chromatograph the residue on silica gel, eluting with 1:1 (v/v) ethyl acetate:hexane to give the title compound as an oil, m/e 290.

Workup

  1. temperatureHeat
  2. temperatureat reflux overnight
  3. customEvaporate
  4. customto give a residue
  5. washChromatograph the residue on silica gel, eluting with 1:1 (v/v) ethyl acetate

Sources & evidence

ORD record
ord-6667037728114557b1ad67f3b10a7eb9
Source dataset
uspto-grants-1988_03
Patent number
US04731364

Reaction notes

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